Epidemiological and clinical features of human coronavirus infections among different subsets of patients
Identifieur interne : 001247 ( Main/Exploration ); précédent : 001246; suivant : 001248Epidemiological and clinical features of human coronavirus infections among different subsets of patients
Auteurs : Tatiane K. Cabeça ; Celso Granato ; Nancy BelleiSource :
- Influenza and Other Respiratory Viruses [ 1750-2640 ] ; 2013.
Abstract
Epidemiological and clinical data of human coronaviruses (
A pan‐coronavirus
Human coronaviruses were detected in 88 of 1137 (7.7%) of the samples. The most frequently detected
Our data provide a novel insight into the epidemiology and clinical knowledge of
Url:
DOI: 10.1111/irv.12101
PubMed: 23462106
PubMed Central: 4634278
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000021
- to stream Pmc, to step Curation: 000021
- to stream Pmc, to step Checkpoint: 000701
- to stream Ncbi, to step Merge: 000369
- to stream Ncbi, to step Curation: 000369
- to stream Ncbi, to step Checkpoint: 000369
- to stream Main, to step Merge: 001249
- to stream Main, to step Curation: 001247
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Epidemiological and clinical features of human coronavirus infections among different subsets of patients</title><author><name sortKey="Cabeca, Tatiane K" sort="Cabeca, Tatiane K" uniqKey="Cabeca T" first="Tatiane K." last="Cabeça">Tatiane K. Cabeça</name><affiliation><nlm:aff id="irv12101-aff-0001"></nlm:aff></affiliation></author><author><name sortKey="Granato, Celso" sort="Granato, Celso" uniqKey="Granato C" first="Celso" last="Granato">Celso Granato</name><affiliation><nlm:aff id="irv12101-aff-0001"></nlm:aff></affiliation></author><author><name sortKey="Bellei, Nancy" sort="Bellei, Nancy" uniqKey="Bellei N" first="Nancy" last="Bellei">Nancy Bellei</name><affiliation><nlm:aff id="irv12101-aff-0001"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23462106</idno><idno type="pmc">4634278</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634278</idno><idno type="RBID">PMC:4634278</idno><idno type="doi">10.1111/irv.12101</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">000021</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000021</idno><idno type="wicri:Area/Pmc/Curation">000021</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000021</idno><idno type="wicri:Area/Pmc/Checkpoint">000701</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000701</idno><idno type="wicri:Area/Ncbi/Merge">000369</idno><idno type="wicri:Area/Ncbi/Curation">000369</idno><idno type="wicri:Area/Ncbi/Checkpoint">000369</idno><idno type="wicri:doubleKey">1750-2640:2013:Cabeca T:epidemiological:and:clinical</idno><idno type="wicri:Area/Main/Merge">001249</idno><idno type="wicri:Area/Main/Curation">001247</idno><idno type="wicri:Area/Main/Exploration">001247</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Epidemiological and clinical features of human coronavirus infections among different subsets of patients</title><author><name sortKey="Cabeca, Tatiane K" sort="Cabeca, Tatiane K" uniqKey="Cabeca T" first="Tatiane K." last="Cabeça">Tatiane K. Cabeça</name><affiliation><nlm:aff id="irv12101-aff-0001"></nlm:aff></affiliation></author><author><name sortKey="Granato, Celso" sort="Granato, Celso" uniqKey="Granato C" first="Celso" last="Granato">Celso Granato</name><affiliation><nlm:aff id="irv12101-aff-0001"></nlm:aff></affiliation></author><author><name sortKey="Bellei, Nancy" sort="Bellei, Nancy" uniqKey="Bellei N" first="Nancy" last="Bellei">Nancy Bellei</name><affiliation><nlm:aff id="irv12101-aff-0001"></nlm:aff></affiliation></author></analytic><series><title level="j">Influenza and Other Respiratory Viruses</title><idno type="ISSN">1750-2640</idno><idno type="eISSN">1750-2659</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="irv12101-sec-0001"><title>Background</title><p>Epidemiological and clinical data of human coronaviruses (<styled-content style="fixed-case">HC</styled-content>o<styled-content style="fixed-case">V</styled-content>s) infections are restricted to span 1–3 years at most. We conducted a comprehensive 9‐year study on <styled-content style="fixed-case">HC</styled-content>o<styled-content style="fixed-case">V</styled-content>s by analyzing 1137 respiratory samples from four subsets of patients (asymptomatic, general community, with comorbidities, and hospitalized) in São Paulo, <styled-content style="fixed-case">B</styled-content>razil.</p></sec><sec id="irv12101-sec-0002"><title>Methods</title><p>A pan‐coronavirus <styled-content style="fixed-case">RT‐PCR</styled-content> screening assay was performed, followed by species‐specific real‐time <styled-content style="fixed-case">RT‐PCR</styled-content> monoplex assays.</p></sec><sec id="irv12101-sec-0003"><title>Results</title><p>Human coronaviruses were detected in 88 of 1137 (7.7%) of the samples. The most frequently detected <styled-content style="fixed-case">HC</styled-content>o<styled-content style="fixed-case">V</styled-content> species were <styled-content style="fixed-case">NL</styled-content>63 (50.0%) and <styled-content style="fixed-case">OC</styled-content>43 (27.3%). Patients with comorbidities presented the highest risk of acquiring coronavirus infection (odds ratio = 4.17; 95% confidence interval = 1.9–9.3), and children with heart diseases revealed a significant <styled-content style="fixed-case">HC</styled-content>o<styled-content style="fixed-case">V</styled-content> infection presence. Dyspnea was more associated with <styled-content style="fixed-case">HC</styled-content>o<styled-content style="fixed-case">V</styled-content>‐229<styled-content style="fixed-case">E</styled-content> infections (66.6%), and cyanosis was reported only in <styled-content style="fixed-case">HC</styled-content>o<styled-content style="fixed-case">V</styled-content>‐<styled-content style="fixed-case">OC</styled-content>43 infections. There were interseasonal differences in the detection frequencies, with <styled-content style="fixed-case">HC</styled-content>o<styled-content style="fixed-case">V</styled-content>‐229<styled-content style="fixed-case">E</styled-content> being predominant in the year 2004 (61.5%) and <styled-content style="fixed-case">HC</styled-content>o<styled-content style="fixed-case">V</styled-content>‐<styled-content style="fixed-case">NL</styled-content>63 (70.8%) in 2008.</p></sec><sec id="irv12101-sec-0004"><title>Conclusions</title><p>Our data provide a novel insight into the epidemiology and clinical knowledge of <styled-content style="fixed-case">HC</styled-content>o<styled-content style="fixed-case">V</styled-content>s among different subsets of patients, revealing that these viruses may cause more than mild respiratory tract disease.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Fields, Bn" uniqKey="Fields B">BN Fields</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Bellei, Nancy" sort="Bellei, Nancy" uniqKey="Bellei N" first="Nancy" last="Bellei">Nancy Bellei</name><name sortKey="Cabeca, Tatiane K" sort="Cabeca, Tatiane K" uniqKey="Cabeca T" first="Tatiane K." last="Cabeça">Tatiane K. Cabeça</name><name sortKey="Granato, Celso" sort="Granato, Celso" uniqKey="Granato C" first="Celso" last="Granato">Celso Granato</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001247 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001247 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= CovidV2
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:4634278
|texte= Epidemiological and clinical features of human coronavirus infections among different subsets of patients
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:23462106" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a CovidV2
| This area was generated with Dilib version V0.6.33. |  |